Congenital Seminal Vesicle Cyst Associated with Ipsilateral Renal Agenesis

PURPOSE: A seminal vesicle cyst in combination with ipsilateral renal agenesis is rarely encountered. We present cases of this disease entity with symptoms, which were treated with a laparoscopic approach as a minimally invasive surgical treatment. MATERIALS AND METHODS: We experienced 4 patients with seminal vesicle cysts and ipsilateral renal agenesis. The mean age was 45.8 years. Chief complaints were perineal pain and hematospermia. Seminal vesicle cysts and remnant ureters were excised by laparoscopic surgery with transperitoneal approaches. RESULTS: The mean operative time was 133.8 minutes. The mean hospital stay was 6.8 days. There were no operative complications or transfusions. CONCLUSION: In our report, patients of congenital seminal vesicle cyst associated with renal agenesis are presented. Laparoscopy is considered a minimal invasive management of these combined anomalies, providing a good image and an easy approach.

Primary congenital lymphedema involving all limbs and genitalia.

Primary congenital lymphedema is the rarest form of primary lymphedema. Lymphedema of the extremities presents at birth and rarely involves the genitalia. There has never been a reported case in Thailand. The authors herby report a case of a 6-year-old boy who presented with progressive swelling of the lower legs since birth. The edema progressed into his scrotum and his arms. There was no history of lymphangitis or cellulites. Physical examination revealed a generalized non-pitting edema of all extremities, more on the right leg than the left leg. Swelling of the scrotum and penis was also detected. A diagnosis of primary congenital lymphedema was confirmed with lymphoscintigraphy.

Genetic role of simple hypospadias

Familial aggregation of simple hypospadias is well documented. The inheritance of this disorder was studied in 71 probands and their families up to the third degree relatives [1107 males] using X2 test for autosomal dominant inheritance and sib-method for autosomal recessive inheritance. An estimation of heritability, a test for multifactorial inheritance, parental consanguinity and average coefficient of inbreeding were done. The results revealed that a higher frequency of the disorder was found among relatives of the probands and diminished as the degree of relationship descended. Data was inconsistent with monogenic modes of inheritance in spite of high consanguinity rate and average coefficient of inbreeding. The results agreed with the multifactorial inheritance. The estimated weighted mean of h2 was 78.08% indicating the importance of the genetic role in the etiology of uncomplicated hypospadias